MEM² - Research

The MEM2 team develops its research activities on the molecular, cellular and pathophysiological mechanisms of tissue mineralization, calcification and ossification.

At the physiological level, the team is particularly intestered in the mechanisms involved in the initiation of mineralization in extracellular vesicles (the so-called matrix vesicles) that are released by hypertrophic chondrocytes.

At the pathological level, the team explores the mechanisms responsible for vascular calcification in atherosclerosis, type 2 diabetes and chronic kidney disease, and for enthesis ossification in spondyloarthritis.