Research areaChemistry at the interface with Biology and Medicine

Some of the ICBMS teams work at the interface between chemistry and life sciences. Their applications are related to medicinal chemistry, particularly in the field of infectiology, oncology and medical imaging, or aspects aimed at a better understanding of biochemical processes such as membrane properties and cell functions, metabolic processes, but also prebiotic chemistry, self-evolving chemical systems and the development of synthetic vaccines based on glycolipid vesicles. To achieve this objective, the researchers use their expertise to develop various innovative tools as well as cross and multidisciplinary approaches, combining theory and experiments, biomimetic systems, molecular probes and selective enzyme inhibitors.

Research topics ICBMS expertises

Chimie médicinale

Chemistry at the interface with Biology and Medicine

Chimiothérapies tropicales

Chemistry at the interface with Biology and Medicine

Glycochimie

Chemistry at the interface with Biology and Medicine

Chimie supramoléculaire

Chemistry at the interface with Biology and Medicine

SysChem: Complex prebiotic and biomolecular systems

Chemistry at the interface with Biology and Medicine

Imagerie

Chemistry at the interface with Biology and Medicine

Membranes biologiques

Chemistry at the interface with Biology and Medicine

Publications Find the most recent scientific contributions

The Use of 5-Hydroxymethylfurfural (5-HMF) in Multi- Component Hantzsch Dihydropyridine Synthesis

Jingjing Jiang, Yves Queneau, Florence Popowycz

ChemSusChem 2024, e202301782

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3D MODEL of an anatomically inert human hand: feasibility study

Lucchino, N.; Pialat, J-B.; Marquette, C.; Courtial, E.; Erhard, L.; Voulliaume, D.; Mojallal, A.; Gazarian, A.

Hand Surgery and Rehabilitation 101709

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Unlocking the Power of Acyl Fluorides: A Comprehensive Guide to Synthesis and Properties

Clémence Bonnefoy, Adrien Gallego, Clément Delobel, Betty Raynal, Maxime Decourt, Emmanuel Chefdeville, Gilles Hanquet, Armen Panossian, Frédéric R. Leroux, Fabien Toulgoat, Thierry Billard

Eur. J. Org. Chem. 2024, 27, e202400142

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Machine learning approaches for the identification of ligands of the autophagy marker LC3

Laurent Soulère, Yves Queneau

Artificial Intelligence Chemistry 1(2) (2023) 100022

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Importance of the 2,6-Difluorobenzamide Motif for FtsZ Allosteric Inhibition: Insights from Conformational Analysis, Molecular Docking and Structural Modifications

T. Barbier, O. Dumitrescu, G. Lina, Y. Queneau, L. Soulère

Molecules, 2023, 28(5), 2055

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